CAS number：1257051-63-0 molecular formula：C23H21ClN6O3
Information THPP-1, a SGC chemical probe, is a potent and orally bioavailable inhibitor of phosphodiesterase 10A (PDE10A) with Ki of 1 nM and 1.3 nM for human and rat PDE10A, respectively. THPP-1 exhibits excellent pharmacokinetic properties in preclinical species.
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| CAS number | 1257051-63-0 | molecular formula | C23H21ClN6O3 |
| molecular weight | 464.9 g/mol | Exact mass | ≥98% |
| PSA | 94.700 Ų | logp | 3.200 |
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