Information RA-190 RA190, a bis-benzylidine piperidon, is a potent, selective and oral effective inhibitor of proteasome ubiquitin receptor RPN13/ADRM1 with anticancer activity. RA190 triggers ER stress response, p53/p21 signaling axis and autophagy in multiple myeloma cells. Targets ADRM1
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RA-190
CAS number:1617495-03-0 molecular formula:C28H23Cl5N2O2
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| Chinese alias | - | ||
| English alias | 4-Piperidinone,1-[(2S)-2-amino-1-oxo-3-phenylpropyl]-3,5-bis[(3,4-dichlorophenyl)methylene]-,hydrochloride (1:1) | ||
| CAS number | 1617495-03-0 | molecular formula | C28H23Cl5N2O2 |
| molecular weight | 596.76 g/mol | Exact mass | 10mM in DMSO |
| PSA | 63.400 Ų | logp | 7.285 |
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