CAS number：1802088-50-1 molecular formula：C21H32N6O3
NCT-501是一种有效的选择性Aldehyde Dehydrogenase 1A1 (ALDH1A1)抑制剂，IC50为40 nM。 Information NCT-501 NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM. Targets ALDH1A1 40 nM In vitro In Caco-2 cell line, NCT-501 exhibits excellent permeability. In vivo In CD1 Mice, NCT-501 is well absorbed and distributed but rapidly metabolized and/or excreted.
| Chinese alias | - | ||
| English alias | 1H-Purine-2,6-dione,8-[[4-(cyclopropylcarbonyl)-1-piperazinyl]methyl]-3,7-dihydro-1,3-dimethyl-7-(3-methylbutyl)- | ||
| CAS number | 1802088-50-1 | molecular formula | C21H32N6O3 |
| molecular weight | 416.52 g/mol | Exact mass | 10mM in DMSO |
| PSA | 82.000 Ų | logp | 0.800 |
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