CAS number：1345098-78-3 molecular formula：C23H24N6O2
Information XMD16-5 XMD16-5 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 16 nmol/L and 77 nmol/L for the D163E and R806Q mutations. Targets TNK2 In vitro XMD16-5 is found to be potent in the inhibition of TNK2 phosphorylation. XMD8-87 and XMD16-5 potently inhibit phosphorylation of TNK2 truncation mutations found in solid tumor types. Cell Research(from reference) Cell lines：293T cells Concentrations：10 nM-5 μM Incubation Time：6 h
| Chinese alias | - | ||
| English alias | 6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one,5,11-dihydro-2-[[4-(4-hydroxy-1-piperidinyl)phenyl]amino]-11-methyl- | ||
| CAS number | 1345098-78-3 | molecular formula | C23H24N6O2 |
| molecular weight | 416.48 g/mol | Exact mass | 10mM in DMSO |
| PSA | 93.600 Ų | logp | 2.967 |
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