BI 3231 是一种有效和选择性的羟基类固醇 17ß-脱氢酶 13 HSD17B13 抑制剂,对 hHSD17B13 和 mHSD17B13 的 IC50 值分别为 1 和 13 nM。BI 3231 具有研究非酒精性脂肪性肝炎 (NASH) 和其他肝脏疾病的潜力。 BI 3231 is a potent and selective hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13) inhibitor, with IC50s of 1 and 13 nM for hHSD17B13 and mHSD17B13, respectively. BI 3231 has the potential for the research of nonalcoholic steatohepatitis (NASH) and other liver diseases.
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BI-3231
CAS number:2894848-07-6 molecular formula:C16H14F2N4O3S
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| Chinese alias | BI3231;compound 45 | ||
| English alias | BI3231;compound 45 | ||
| CAS number | 2894848-07-6 | molecular formula | C16H14F2N4O3S |
| molecular weight | 380.37 g/mol | Exact mass | - |
| PSA | - | logp | - |
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