Moracin P is a 2-arylbenzofuran isolated from the Mori Cortex Radicis. Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin P reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin P has neuroprotective and anti-inflammatory effects . In Vitro Moracin P enhances cell viability in dose-dependent manner against oxygen-glucose deprivation (OGD)-induced cell death in neuroblastoma SH-SY5Y cells with an EC 50 value of 10.4 μM. Moracin P reduces ROS production in OGD-induced cell death (IC 50 values of 1.9 μM). Consequently, reactive oxygen species (ROS) are overexpressed in OGD-induced cells and Moracin P reduces ROS induced by OGD in dosedependent manner. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid
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Moracin P
CAS number：102841-46-3 molecular formula：C19H18O5
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| Chinese alias | 桑树素P | ||
| English alias | - | ||
| CAS number | 102841-46-3 | molecular formula | C19H18O5 |
| molecular weight | 326.34 g/mol | Exact mass | - |
| PSA | - | logp | - |
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