NSC689857 is a potent EGFR and SCF SKP2 inhibitor with an IC 50 value of 36 μM for Skp2-Cks1. NSC689857 can inhibit p27 ubiquitylation (IC 50 =30 μM). NSC689857 has varied activity across cancer types, with more activity against leukemia cell lines than others Form:Solid IC50& Target:IC 50 : 36 μM (Skp2-Cks1), 30 μM (p27 ubiquitylation)
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NSC689857
CAS number:241127-79-7 molecular formula:C25H29NO4
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 241127-79-7 | molecular formula | C25H29NO4 |
| molecular weight | 407.50 g/mol | Exact mass | ≥99% |
| PSA | 78.800 Ų | logp | 5.400 |
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