CAS number：802906-73-6 molecular formula：C18H13ClFN3
Basimglurant (RG7090) 是高效，选择性有口服活性的mGlu5负变构调节剂，Kd值为1.1 nM。 Basimglurant (RG7090) is a potent, selective mGlu5 negative allosteric modulator with a Kd of 1.1 nM. Basimglurant is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
| Chinese alias | 2-氯-4-((1-(4-氟苯基)-2,5-二甲基-1H-咪唑-4-基)乙炔基)吡啶 | 巴辛格鲁兰特 | ||
| English alias | CTEP Derivative | RG7090 | RG-7090 | 2-Chloro-4-((1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazol-4-yl)ethynyl)pyridine | RO-4917523 | ||
| CAS number | 802906-73-6 | molecular formula | C18H13ClFN3 |
| molecular weight | 325.8 g/mol | Exact mass | - |
| PSA | 30.700 Ų | logp | 4.5 |
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