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Apimostinel

CAS number:1421866-48-9    molecular formula:C25H37N5O6

overview

compound introduction

Apimostinel (NRX-1074; AGN-241660) is an orally active NMDA receptor partial agonist. In Vitro Apimostinel (NRX-1074) modulates the NMDA receptor in a similar fashion to GLYX-13, but has a synthetic modification to one of the amino acids, conferring increased potency and oral bioavailability. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo In preclinical models the two compounds both appear to be highly efficacious across a number of CNS disorders . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

Specs

Chinese alias阿莫司汀
English alias(2R)-1-[(2S)-1-[(2S,3R)-2-amino-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]-N-[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]-2-benzylpyrrolidine-2-carboxamide | DB11784 | SCHEMBL14682282 | Apimostinel [USAN] | 1421866-48-9 | L-THREONYL-L-PROLYL-2-BENZYL-L-PROL
CAS number1421866-48-9molecular formulaC25H37N5O6
molecular weight503.59 g/molExact mass≥98%
PSA179.000 Ųlogp-1

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