compound introduction
Foliglurax monohydrochloride (PXT002331 monohydrochloride) is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator ( mGluR4 PAM) , with an EC 50 of 79 nM Antiparkinsonian effect In Vitro Foliglurax, a highly selective and potent mGlu4 receptor PAM with a marked brain-penetrance feature, might revolutionize the field of mGlu4 receptor drug targeting in CNS disorders. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:mGlu 4 79 nM (EC 50 )
