琥珀酰亚胺酯(NHS,胺反应活性)官能化环辛烷衍生物,用来将环辛烷部分插入含有化合物或生物分子的氨基找那个。环辛烷可以用于种促进免铜电极化学环加成反应。这一聚乙二醇会和叠氮官能化化合物或生物分子反应,而不需要Cu(I)催化,就能形成稳定的三唑连接。 应用包括:蛋白质-多肽偶联物;抗体-酶或抗体药物偶联物;蛋白质或多肽-寡核苷酸偶联物;表面修饰。 聚乙二醇-PEG4-N-氢化琥珀酰亚胺酯可以通过少铜点击反应,用来合成前列腺特异性膜抗体(PSMA)目标单光子发射计算体层摄影(SPECT)试剂。 Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. Product Describtion: DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs
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DBCO-PEG4-NHS Ester
CAS number:1427004-19-0 molecular formula:C34H39N3O10
overview
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Specs
| Chinese alias | DBCO-PEG4-琥珀酰亚胺脂 | 20-(11,12-二脱氢二苯并[b,f]吖辛因-5(6H)-基)-17,20-二氧代-4,7,10,13-四氧杂-16-氮杂二十酸2,5-二氧代-1-吡咯烷基酯 | 二苯并环辛炔-PEG4-琥珀酰亚胺酯 | ||
| English alias | Dibenzocyclooctyne-PEG4-Nhydroxysuccinimidyl ester | DBCO-PEG4-NHS ester | DBCO-PEG4-SE | DBCO-PEG4-succinimidyl ester | DBCO-NH-PEG4-CH2CH2COONHS ester | ||
| CAS number | 1427004-19-0 | molecular formula | C34H39N3O10 |
| molecular weight | 649.70 g/mol | Exact mass | ≥95% |
| PSA | 150.000 Ų | logp | 0.400 |
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