CAS number：2172819-74-6 molecular formula：C28H38N4O6S
(S,R,S)-AHPC-C4-COOH是一种合成的 E3 连接酶配体-linker 偶联物，包含基于 (S,R,S)-AHPC 的 VHL 配体和 1 个 linker。用于合成 EED 的靶向 PROTAC (S,R. S)-AHPC-pentanoic-acid is a synthetic compound that incorporate an E3 ligase ligand with a linker to empower PROTAC drug research & discovery. PEG spacer increase aqueous solubility.
| Chinese alias | - | ||
| English alias | 6-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-6-oxohexanoic acid | VH032-linker 5 | (S,R,S)-AHPC-C4-COOH | ||
| CAS number | 2172819-74-6 | molecular formula | C28H38N4O6S |
| molecular weight | 558.69 g/mol | Exact mass | ≥98% |
| PSA | 177.000 Ų | logp | 2.500 |
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