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N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid

CAS number:2183440-74-4    molecular formula:C29H55N5O13

overview

compound introduction

N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid 是一种点击化学试剂。它含有 Azide 基团,可以和含有 Alkyne 基团的分子发生铜催化的叠氮-炔环加成反应(CuAAc)。它还可以和含有 DBCO 或 BCN 基团的分子发生环张力驱动的炔-叠氮环加成反应 (SPAAC)。 N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Specs

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CAS number2183440-74-4molecular formulaC29H55N5O13
molecular weight681.8 g/molExact mass≥98%
PSA-logp-

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