CAS number：828243-30-7 molecular formula：C17H23NO4
Application： 3-(1-(tert-Butoxycarbonyl)piperidin-4-yl)benzoic acid is a 4-aryl piperidine useful as a semi-flexible linker in PROTAC development for targeted protein degradation. Incorporation of rigidity into the linker region of bifunctional protein degraders may impact the 3D orientation of the degrader and thus ternary complex formation as well as optimization of drug-like properties.
| Chinese alias | 3-(1-(叔丁氧羰基)哌啶-4-基)苯甲酸 | ||
| English alias | 4-(3-CARBOXY-PHENYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER | 4-(3-carboxyphenyl)piperidine-1-carboxylic acid tert-butyl ester | SCHEMBL226123 | 3-(1-(tert-Butoxycarbonyl)piperidin-4-yl)benzoic acid, AldrichCPR | AKOS015998702 | MFCD02178898 | DTXS | ||
| CAS number | 828243-30-7 | molecular formula | C17H23NO4 |
| molecular weight | 305.37 g/mol | Exact mass | ≥98% |
| PSA | 66.800 Ų | logp | 2.900 |
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