compound introduction
Palbociclib (PD-0332991) is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity.
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Palbociclib
Dangerous GoodsCAS number：571190-30-2 molecular formula：C24H29N7O2
overview
Specs
| Chinese alias | 6-乙酰基-8-环戊基-5-甲基-2-[[[5-(1-哌嗪基)-2-吡啶基]氨基]吡啶基[2,3-d]嘧啶-7(8H)-酮 | 爱博新 | 帕博昔利 | ||
| English alias | PD0332991 | PD991 | PF 00080665 | PF-00080665 | PF00080665 | 6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | Palbociclib- Bio-X | palbociclibum | R 802 (bactericide) | SY026143 | 6-ACETYL-8-CYCLOPEN | ||
| CAS number | 571190-30-2 | molecular formula | C24H29N7O2 |
| molecular weight | 447.53 g/mol | Exact mass | - |
| PSA | 103.000 Ų | logp | 1.8 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS06 , GHS08 , GHS09 , GHS07
Signal word：
Danger
Hazard Statement：
H301: 吞咽会中毒 H341: 怀疑引起遗传缺陷 H373: 通过长时间或反复暴露对器官造成损害 H411: 对水生生物有毒并具有长期持续影响 H302: 吞食有害 H372: 通过长时间或反复暴露对器官造成损害 H360: 可能损害生育力或未出生的孩子 H361: 怀疑破坏生育力或未出生的孩子
Statement of Preventive Measures：
P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P281: 根据需要使用个人防护设备。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P391: 收集溢出物 P330: 漱口 P203: 使用前，获取、阅读并遵守所有安全说明。 P301+P316: 如果吞咽：立
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