BrettPhos Pd G4是一种N-取代的2-氨基联苯钯甲烷磺酸酯预催化剂。它是第四代(G4)Buchwald预催化剂,与第三代(G3)预催化剂相似,只是联苯主链上的氨基被甲基化了。这种修饰可有助于防止使用第三代预催化剂的局限性。它具有空气、湿度和热稳定性并在常用有机溶剂中具有良好的溶解性。BrettPhos Pd G4在交叉偶联反应中非常有用。它的一些出色特性包括更低的催化剂负载量、更短的反应时间、有效的催化活性物种形成以及对配体:钯比例的精确控制。 Technical Note: 1. Catalyst used for the N-arylation of amines. Reference: 1. J. Org. Chem., 2014, 79, 4161
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Methanesulfonato(2-dicyclohexylphosphino-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-methylamino-1,1'-biphenyl-2-yl)palladium(II)
CAS number:1599466-83-7 molecular formula:C49H68NO5PPdS
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compound introduction
Specs
| Chinese alias | - | ||
| English alias | Methanesulfonato(2-dicyclohexylphosphino-3,6-dimethoxy-2'',4'',6''-tri-i-propyl-1,1''-biphenyl)(2''-methylamino-1,1''-biphenyl-2-yl)palladium(II) | BrettPhos Pd G4 | (SP-4-3)-[Dicyclohexyl[3,6-dimethoxy-2′,4′,6′-tris(1-methylethyl)[1,1′-biphenyl]-2-yl]pho | ||
| CAS number | 1599466-83-7 | molecular formula | C49H68NO5PPdS |
| molecular weight | 920.53 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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1599466-83-7 | BrettPhos Pd G4.pdf





