Eribulin (B1939) 是非紫杉烷微管动力学抑制剂,具有抗癌活性,通过防止细胞分裂过程中微管的延长和缩短来抑制微管蛋白亚基的聚合。Eribulin 可用于研究转移性乳腺癌和实体瘤。 Eribulin (B1939) is a nonpaclitaxel microtubule kinetic inhibitor with anticancer activity that inhibits polymerization of microtubule protein subunits by preventing lengthening and shortening of microtubules during cell division.Eribulin is used in the study of metastatic breast cancer and solid tumors.
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Eribulin
CAS number:253128-41-5 molecular formula:C40H59NO11
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| Chinese alias | 艾日布林 | 艾立布林 | 艾瑞布林 | ||
| English alias | UFNVPOGXISZXJD-JBQZKEIOSA-N | AMY22567 | eribuline | LR24G6354G | 2-(3-Amino-2-hydroxypropyl)hexacosahydro-3-methoxy-26-methyl-20,27-bis(methylene)11,15-18,21-24,28-triepoxy-7,9-ethano-12,15-methano-9H,15H-furo(3,2-i)furo(2',3'-5,6)pyrano(4,3-b)(1,4)dioxa | ||
| CAS number | 253128-41-5 | molecular formula | C40H59NO11 |
| molecular weight | 729.9 g/mol | Exact mass | - |
| PSA | 146.000 Ų | logp | 1.100 |
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