All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry

Tubastatin A HCl

CAS number:1310693-92-5    molecular formula:C20H21N3O2.HCl

overview

compound introduction

Tubastatin A盐酸盐是HDAC6选择性抑制剂,IC50为15 nM,比对其它亚型的抑制性高1000倍(相对HDAC8是57倍)。An HDAC6 inhibitor Tubastatin A HCl is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay. It is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). An HDAC6 inhibitor

Specs

Chinese aliasTubastatin A 盐酸盐
English aliasBCP02887 | 4-((2-Methyl-3,4-dihydro-1H-pyrido(4,3-b)indol-5-yl)methyl)benzenecarbohydroxamic acid hydrochloride | N-hydroxy-4-[(2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)methyl]benzamide;hydrochloride | TSA HCl | UNII-UHCM2AYJVX | CCG-268318 | SW219
CAS number1310693-92-5molecular formulaC20H21N3O2.HCl
molecular weight371.86 g/molExact mass≥98%
PSA57.500 Ųlogp-

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

No safety information yet

Production methods and uses

No production method and use information yet

Related

upstream information

No upstream information yet

downstream information

No downstream information yet

MSDS

Found 0 shareMSDS