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Elaiophylin

CAS number:37318-06-2    molecular formula:C54H88O18

overview

compound introduction

Elaiophylin大环内脂类抗菌素,作用于恶性疟原虫K1a 和布氏布锥虫GUTat 3.1 品系,具有抗原生动物活性,IC50分别为370 ng/mL和460 ng/mL。A macrolide antibiotic with immunosuppresive activity. Elaiophylin shows antiprotozoal activity against Plasmodium falciparum K1a and Trypanosoma brucei brucei GUTat 3.1 strains with IC50 of 0.36 μM and 0.45 μM, respectively. A macrolide antibiotic with immunosuppresive activity.

Specs

Chinese alias洋橄榄叶素
English aliasAntibiotic 5001B | Azalomycin-B | EX-A3078 | Antibiotic 56-62 | Azalomycin B | (3E,5E,7S,8S,11E,13E,15S,16S)-8,16-bis{(2S,3R,4S)-4-[(2R,4R,5R,6R)-4-{[(2R,4S,5S,6S)-4,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-5-ethyl-2-hydroxy-6-methyltetrahydro-2H
CAS number37318-06-2molecular formulaC54H88O18
molecular weight1025.27 g/molExact mass≥95%
PSA270.000 Ųlogp7.000

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