CAS number：422513-13-1 molecular formula：C29H32N4O3S
Hesperadin是ATP竞争性Aurora B抑制剂，IC50为250 nM。 Hesperadin potently inhibits Aurora B with IC50 of 250 nM in a cell-free assay. It markedly reduces the activity of AMPK, Lck, MKK1, MAPKAP-K1, CHK1 and PHK while it does not inhibit MKK1 activity in vivo.
| Chinese alias | N-(2,3-二氢-2-氧代-3-((3Z)-苯基((4-(1-哌啶基甲基)苯基)氨基)亚甲基)-1H-吲哚-5-基)乙磺酰胺 | ||
| English alias | BDBM192753 | N-[(3Z)-2-oxo-3-[phenyl-[4-(piperidin-1-ylmethyl)anilino]methylidene]-1H-indol-5-yl]ethanesulfonamide | AC-35920 | hesperadine | SW219406-1 | MFCD18074526 | DTXSID00195086 | N-[2-hydroxy-3-[C-phenyl-N-[4-(piperidin-1-ylmethyl)phenyl]carbonimi | ||
| CAS number | 422513-13-1 | molecular formula | C29H32N4O3S |
| molecular weight | 516.67 g/mol | Exact mass | - |
| PSA | 106.000 Ų | logp | 5.200 |
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