Information Dasabuvir (ABT-333) Dasabuvir (ABT-333) is a non-nucleoside inhibitor of NS5B viral RNA-dependent RNA polymerase that inhibits recombinant NS5B polymerases derived from HCV genotype 1a and 1b clinical isolates with IC50 values between 2.2 and 10.7 nM. It is at least 7,000-fold selective for the inhibition of HCV genotype 1 polymerases over human/mammalian polymerases.
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Dasabuvir (ABT-333)
CAS number:1132935-63-7 molecular formula:C26H27N3O5S
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| Chinese alias | - | ||
| English alias | Dasabuvir | 1132935-63-7 | ABT-333 | N-(6-(3-(tert-butyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl)naphthalen-2-yl)methanesulfonamide | ABT333 | Dasabuvir [INN] | Dasabuvir (ABT-333) | CHEBI:85182 | ABT 333 | Dasabuvir sodium monohydrat | ||
| CAS number | 1132935-63-7 | molecular formula | C26H27N3O5S |
| molecular weight | 493.57 g/mol | Exact mass | - |
| PSA | 113.000 Ų | logp | 3.492 |
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