Information Solithromycin (CEM-101, OP-1068), belonging to the well-known class of macrolide antibiotics that also includes azithromycin, is a potentbacterial protein synthesisinhibitor. Application： Solithromycin is a highly potent next-generation macrolide, the first fluoroketolide, which has potent activity against most macrolide-resistant strains. In vitro and in vivo studies have shown potent activity against S. pneumoniae as well as an extended spectrum of activity against CA-MRSA, enterococci, Mycobacterium avium and in animal models of malaria. It is also active against atypical bacteria, such as Legionella, Chlamydophila, Chlamydia, Mycoplasmaand Ureaplasma and against gonococci and other organisms that cause genitourinary tract infections.
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Solithromycin
CAS number：760981-83-7 molecular formula：C43H65FN6O10
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Specs
| Chinese alias | - | ||
| English alias | CEM 101 | AKOS032947334 | (1R,2R,4R,6R,7R,8R,10S,13R,14S)-17-[4-[4-(3-aminophenyl)triazol-1-yl]butyl]-7-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-13-ethyl-10-fluoro-6-methoxy-2,4,6,8,10,14-hexamethyl-12,15-dioxa-17-azabicyclo[12.3.0 | ||
| CAS number | 760981-83-7 | molecular formula | C43H65FN6O10 |
| molecular weight | 845.01 g/mol | Exact mass | - |
| PSA | 198.000 Ų | logp | 4.802 |
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