compound introduction
CCF0058981 (CCF981) 是一种3-氯苯基类似物，一种非共价SARS-CoV-2 3CLpro (SC2) 抑制剂，IC50为68 nM。CCF0058981抑制SC1 (SARS-CoV-1 3CLpro)，IC50为19 nM。CCF0058981具有抗病毒功效，具有用于COVID-19研究的潜力。 CCF0058981 (CCF981), 3-chlorophenyl analogue, is a noncovalent SARS-CoV-2 3CLpro (SC2) inhibitor with an IC50 of 68 nM. CCF0058981 inhibits SC1 (SARS-CoV-1 3CLpro) with an IC50 of 19 nM. CCF0058981 has antiviral efficacy and has the potential for COVID-19 research.
