compound introduction
SARS-CoV-IN-3 is an effective inhibitor of SARS-CoV replication. SARS-CoV-IN-3 shows anti-Coronavirus activity with an EC 50 of 3.6 μM in Vero cells. SARS-CoV-IN-3 inhibits the 3D7 and W2 strains of P. falciparum with IC 50 s of 11.7 and 20.4 nM; and IC 90 s of 29.19 and 56 nM; respectively. SARS-CoV-IN-3 reduces HIV-1 -induced cytopathic effect with an EC 50 of 10 μM in MT-4 cells In Vitro SARS-CoV-IN-3 (Compound 4) inhibits in vitro growth of Plasmodium falciparum far better than Chloroquine (CQ). MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Plasmodium HIV-1
