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FK-960

CAS number:133920-70-4    molecular formula:C13H16FN3O2

overview

compound introduction

FK960 是一种潜在的抗痴呆剂,通过增强胆碱能神经传递,来逆转感觉刺激引起的脑血流量 (rCBF) 减少。在猕猴实验中,毒扁豆碱能够完全消除振动触觉刺激增加的感觉皮层的 rCBF。FK960 (1-1000 μg/kg) 则可以恢复被消除的 rCBF 反应,作用时间可持续 1 小时。然而,FK960 不能恢复由 HA-966消除的 rCBF 反应,表明其功能不依赖于非谷氨酸能神经传递。

Specs

Chinese alias-
English alias-
CAS number133920-70-4molecular formulaC13H16FN3O2
molecular weight265.28 g/molExact mass-
PSA52.700 Ųlogp0.800

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