Spiradoline mesylate (U-62066 mesylate) 是一种芳基乙酰胺,是一种选择性 kappa 阿片受体 (κ-opioid receptor, KOR) 激动剂,在豚鼠中的Ki为 8.6 nM。Spiradoline mesylate 对 μ 和 δ 受体的 Ki值分别为 252 nM 和 9400 nM。Spiradoline mesylate 具有强效的利尿,止痛,抗心律失常,镇咳,神经保护作用,并易于穿过血脑屏障。
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Spiradoline Mesylate
CAS number:87173-97-5 molecular formula:C23H34Cl2N2O5S
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 87173-97-5 | molecular formula | C23H34Cl2N2O5S |
| molecular weight | 521.500 g/mol | Exact mass | ≥99% |
| PSA | 95.500 Ų | logp | - |
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