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4-((1H-Indol-7-yl)carbamoyl)phenyl diethylcarbamate

CAS number:1237541-73-9    molecular formula:

overview

compound introduction

NAB-14 是一种有效的、选择性的、具有口服活性和非竞争性的GluN2C/2D拮抗剂,对 GluN1/GluN2D 的IC50为 580 nM。NAB-14 对重组 GluN2C 和 GluN2D 的选择性比 GluN2A 和 GluN2B 高 800 倍。NAB-14 可以穿过血脑屏障。

Specs

Chinese alias-
English alias-
CAS number1237541-73-9molecular formula
molecular weight351.400 g/molExact mass≥98%
PSA74.400 Ųlogp3.400

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