NAB-14 是一种有效的、选择性的、具有口服活性和非竞争性的GluN2C/2D拮抗剂,对 GluN1/GluN2D 的IC50为 580 nM。NAB-14 对重组 GluN2C 和 GluN2D 的选择性比 GluN2A 和 GluN2B 高 800 倍。NAB-14 可以穿过血脑屏障。
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4-((1H-Indol-7-yl)carbamoyl)phenyl diethylcarbamate
CAS number:1237541-73-9 molecular formula:
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 1237541-73-9 | molecular formula | |
| molecular weight | 351.400 g/mol | Exact mass | ≥98% |
| PSA | 74.400 Ų | logp | 3.400 |
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