Benzquinamide (P2647) 是一种止吐剂, 并可以与α2A,α2B, 以及α2C肾上腺素能受体 (α2-AR) 结合,Ki值分别为 1,365, 691 和 545 nM。Benzquinamide 还抑制 P-糖蛋白介导的药物流出,并增强多药耐药细胞中抗癌药物的细胞毒性。
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3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride
CAS number:113-69-9 molecular formula:C22H33ClN2O5
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 113-69-9 | molecular formula | C22H33ClN2O5 |
| molecular weight | 440.96 g/mol | Exact mass | ≥99% |
| PSA | 68.300 Ų | logp | - |
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