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3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride

CAS number:113-69-9    molecular formula:C22H33ClN2O5

overview

compound introduction

Benzquinamide (P2647) 是一种止吐剂, 并可以与α2A,α2B, 以及α2C肾上腺素能受体 (α2-AR) 结合,Ki值分别为 1,365, 691 和 545 nM。Benzquinamide 还抑制 P-糖蛋白介导的药物流出,并增强多药耐药细胞中抗癌药物的细胞毒性。

Specs

Chinese alias-
English alias-
CAS number113-69-9molecular formulaC22H33ClN2O5
molecular weight440.96 g/molExact mass≥99%
PSA68.300 Ųlogp-

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