(-)Clausenamide is an active alkaloid isolated from the leaves of Clausena lansium (Lour.) Skeels,and improves cognitive function in both normal physiological and pathological conditions.(-)Clausenamide inhibits β-amyloid (Aβ) toxicity, blocking neurofibrillary tangle formation by inhibiting the phosphorylation of tau protein. (-)Clausenamide exerts a significant neuroprotective activity against Aβ 25-35. (-)Clausenamide can be used for researching Alzheimer's disease (AD).
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(-)Clausenamide
CAS number:201529-58-0 molecular formula:C18H19NO3
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 201529-58-0 | molecular formula | C18H19NO3 |
| molecular weight | 297.35 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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