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(1S,2S)-ML-SI3

CAS number:2563870-87-9    molecular formula:C23H31N3O3S

overview

compound introduction

(1S,2S)-ML-SI3 is a trans-isomer of ML-SI3 that targets all three isoforms of TRPML. (1S,2S)-ML-SI3 is an activator of TRPML2 and TRPML3 ( EC 50 =2.7 μM/10.8 μM) and a potent inhibitor of TRPML1 ( IC 50 =5.9 μM).

Specs

Chinese alias-
English alias-
CAS number2563870-87-9molecular formulaC23H31N3O3S
molecular weight429.58 g/molExact mass≥99%
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