5-HT6 inverse agonist 1 (Compound 33) is an antagonist for 5-HT6 receptor with a K i of 23 nM and a K b of 6.62 nM. 5-HT6 inverse agonist 1 inhibits the 5-HT6R mediated Cdk5 and mTOR signaling pathway. 5-HT6 inverse agonist 1 reduces tactile hypersensitivity in spinal nerve ligation (SNL)-induced rat model.
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5-HT6 inverse agonist 1
CAS number:2727088-38-0 molecular formula:C22H22Cl2FN3O3S
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 2727088-38-0 | molecular formula | C22H22Cl2FN3O3S |
| molecular weight | 498.40 g/mol | Exact mass | - |
| PSA | - | logp | - |
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