CAS number：257879-35-9 molecular formula：C24H21N5O2
PKC |β|抑制剂是一种苯胺-单吲哚基马来酰亚胺化合物，可作为PKCβ同工酶的强效和ATP竞争性抑制剂（对于人PKCβII和βI，IC | 50 | = 5 nM和21 nM），并且对PKCα，PKCγ， PKCε（IC | 50 | = 331 nM，分别> 1μM和2.8μM）。 PKC|β|Inhibitor is an anilino-monoindolylmaleimide compound that acts as a potent and ATP-competitive inhibitor of PKCβ isozymes (IC|50|= 5 nM and 21 nM for human PKCβII and βI) and displays greater selectivity over PKCα, PKCγ,PKCε (IC|50|= 331 nM, > 1 μM, and 2.8 μM, respectively).
| Chinese alias | - | ||
| English alias | PKCbeta inhibitor 1 | CCG-206785 | SCHEMBL7841474 | 3-Anilino-4-(1-(3-imidazol-1-ylpropyl)indol-3-yl)pyrrole-2,5-dione | CHEBI:94140 | PKCss inhibitor | PKCb inhibitor 1 | AKOS040759380 | K00248 | KUN79359 | PKC beta | 3-(1-(3-(1H-Imidazol-1-yl)propyl)-1H | ||
| CAS number | 257879-35-9 | molecular formula | C24H21N5O2 |
| molecular weight | 411.46 g/mol | Exact mass | - |
| PSA | 81.000 Ų | logp | 2.800 |
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