3-(4-Pyridyl)indole (Rockout) 是一种 Rho 激酶 (ROCK) 抑制剂,IC50 值为 25 μM。在伤口愈合试验中,3-(4-Pyridyl)indole 可以抑制起泡并导致肌动蛋白应力纤维溶解。 3-(4-Pyridyl)indole (Rockout) is a Rho-kinase (ROCK) inhibitor, with an IC50 of 25 μM. 3-(4-Pyridyl)indole can inhibit blebbing and cause dissolution of actin stress fibers in a wound healing assay.
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3-(4-Pyridyl)indole
CAS number:7272-84-6 molecular formula:C13H10N2
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| Chinese alias | Rho 激酶抑制剂 III、Rockout | ||
| English alias | 3-(4-Pyridinyl)-1H-indole; Indole, 3-(4-pyridyl)- (6CI,7CI,8CI) | 3-(PYRIDIN-4-YL)INDOLE | rockout | CCG-206787 | ChemDiv2_000332 | 3-(4-Pyridyl)-1H-indole | MLS000029246 | Oprea1_292323 | SCHEMBL238277 | HMS2280K08 | ROCK Inhibitor (Rockout) | AKOS000533 | ||
| CAS number | 7272-84-6 | molecular formula | C13H10N2 |
| molecular weight | 194.23 g/mol | Exact mass | - |
| PSA | 28.700 Ų | logp | 2.800 |
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