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Lobeglitazone

CAS number:607723-33-1    molecular formula:

overview

compound introduction

Lobeglitazone 是一种新型噻唑烷二酮。Lobeglitazone 是口服有效的PPAR的激动剂,对PPARγ和PPARα的 EC50为 137.4 nM 和 546.3 nM。Lobeglitazone 是ERK/JNK/Smad/NF-κB信号通路的抑制剂。Lobeglitazone 具有抗炎、抗糖尿病、抗纤维化和抗动脉粥样硬化的活性。

Specs

Chinese alias-
English alias-
CAS number607723-33-1molecular formula
molecular weight480.500 g/molExact mass-
PSA128.000 Ųlogp4.300

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