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Polyinosinic-polycytidylic acid potassium salt

CAS number:31852-29-6    molecular formula:(C10H13N4O8P)x.(C9H14N3O8P)x.xK

overview

compound introduction

本品需要离子强度,以维持双链结构。用水复溶至浓度约为10 mg/mL,获得溶于生理磷酸盐缓冲溶液的多核苷酸。TLR3可识别双链RNA,是病毒病原体免疫应答的主要效应物。 聚肌苷酸-聚胞苷酸 (Poly(I) · Poly(C))是一种双链均聚物,可作为模型RNA,用于研究在TLR3水平下的细胞信号传导。 Poly(IC)是TRIF依赖型toll样受体3(TLR3)的配体。 Product Description: TLR3 recognizes double-stranded RNA and is a major effector of the immune response against viral pathogens. Polyinosinic–polycytidylic acid (Poly(I) • Poly(C)) is a double-stranded homopolymer used as a model RNA to study cell signaling at the level of TLR3. Poly(IC) is a TRIF-dependent toll-like receptor-3 (TLR3) ligand.

Specs

Chinese alias-
English aliasPoly (I:C), Poly(I) · Poly(C)
CAS number31852-29-6molecular formula(C10H13N4O8P)x.(C9H14N3O8P)x.xK
molecular weight-Exact mass≥99%(TLC)
PSA-logp-

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