compound introduction
A-1155463是高效选择性的 BCL-XL 抑制剂，在Molt-4细胞中的EC50值为70 nM。 A-1155463 is a highly potent and selective BCL-XL inhibitor with an EC50 of 70 nM in Molt-4 cell.
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A-1155463
CAS number：1235034-55-5 molecular formula：C35H32FN5O4S2
overview
Specs
| Chinese alias | 2-[8-[(2-苯并噻唑基氨基)羰基]-3,4-二氢-2(1H)-异喹啉基]-5-[3-[4-[3-(二甲基氨基)-1-丙炔基-1]]-2-氟苯氧基]丙基]-4-噻唑羧酸 | ||
| English alias | A 1155463 | 2-(8-(Benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-5-(3-(4-(3-(dimethylamino)prop-1-yn-1-yl)-2-fluorophenoxy)propyl)thiazole-4-carboxylic acid | ||
| CAS number | 1235034-55-5 | molecular formula | C35H32FN5O4S2 |
| molecular weight | 669.79 g/mol | Exact mass | ≥97% |
| PSA | 164.000 Ų | logp | 4.800 |
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