结合Hec1的抑制剂,抑制其与Nek2和动植物的结合。导致有丝分裂停滞并抑制乳腺癌细胞系的增殖(GI50 = 10-20μM)。 Inhibitor that binds Hec1, inhibiting its association with Nek2 and kinetochores. Causes arrest of mitosis and inhibits proliferation in breast cancer cell lines (GI50= 10-20 μM).
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INH1
CAS number:313553-47-8 molecular formula:C18H16N2OS
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Specs
| Chinese alias | - | ||
| English alias | Benzamide,N-[4-(2,4-dimethylphenyl)-2-thiazolyl]- | INH1 | LM-3287 | N-(4-(2,4-dimethylphenyl) -2-thiazolyl)benzamide | AC-33047 | HY-16660 | Q18350699 | N-(4-(2,4-dimethylphenyl)thiazol-2-yl)benzamide | CCG-267565 | MFCD01356769 | N-[4-(2,4-dimethylpheny | ||
| CAS number | 313553-47-8 | molecular formula | C18H16N2OS |
| molecular weight | 308.40 g/mol | Exact mass | 10mM in DMSO |
| PSA | 70.200 Ų | logp | 4.500 |
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