CAS number：151358-47-3 molecular formula：C23H18N2O
DIM-C-pPhOH 是核受体 4A1 (NR4A1) 拮抗剂。DIM-C-pPhOH 抑制癌细胞的生长和 mTOR 信号传导，诱导细胞凋亡和细胞应激。DIM-C-pPhOH 可降低细胞增殖，对 ACHN 细胞和 786-O 细胞的 IC50 值分别为 13.6 μM 和 13.0 μM。 product description： DIM-C-pPhOH is a nuclear receptor 4A1 (NR4A1) antagonist. DIM-C-pPhOH inhibits cancer cell growth and mTOR signaling, induce apoptosis and cellular stress. DIM-C-pPhOH reduces cell proliferation with IC50 values of 13.6 μM and 13.0 μM for ACHN cells and 786-O cells, respectively。
| Chinese alias | 1,1-双(3'-吲哚基)-1-(对羟基苯基)甲烷 | 4-[二(1H-吲哚-3-基)甲基]苯酚 | (4-羟基苯基)双(1H-吲哚-3-基)甲烷 | ||
| English alias | 1,1-Bis(3'-indolyl)-1-(p-hydroxyphenyl)methane | C-DIM8 | (4-Hydroxyphenyl)bis(1H-indol-3-yl)methane | (4-Hydroxyphenyl)bis(1H-indol-3-yl)methane | 4-(Di-1H-indol-3-ylmethyl)phenol | 7,7-Bis(3-indolyl)-p-cresol | CDIM8 | ||
| CAS number | 151358-47-3 | molecular formula | C23H18N2O |
| molecular weight | 338.408 g/mol | Exact mass | - |
| PSA | 51.800 Ų | logp | 5.200 |
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