CAS number：108885-68-3 molecular formula：C36H46O14
Taccalonolide A is a microtubule stabilizer, which is a steroid isolated from Tacca chantrieri , with cytotoxic and antimalarial activities Taccalonolide A causes G 2 -M accumulation, Bcl-2 phosphorylation and initiation of apoptosis Taccalonolide A is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug resistance protein 7 (MRP7), with an IC 50 of 622 nM for SK-OV-3 cells Form:Solid IC50& Target:microtubule
| Chinese alias | 塔卡洛内酯A | ||
| English alias | A904550 | CHEBI:9388 | AKOS037515195 | 16,24-Cycloergost-22-en-26-oicacid, 1,11,12,15-tetrakis(acetyloxy)-2,3-epoxy-7,23,25-trihydroxy-6-oxo-, g-lactone, (1a,2a,3a,5a,7b,11a,12a,15a,16b,24b,25S)- | Q27108373 | AC1L9BGV | DTXSID80910895 | PTTJLTMUKRRHAT-VJ | ||
| CAS number | 108885-68-3 | molecular formula | C36H46O14 |
| molecular weight | 702.74 g/mol | Exact mass | ≥99% |
| PSA | 202.000 Ų | logp | 1.700 |
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