(E)-[6]-Dehydroparadol, an oxidative metabolite of [6]-Shogaol , is a potent Nrf2 activator. (E)-[6]-Dehydroparadol can inhibit the growth and induce the apoptosis of human cancer cells In Vitro (E)-[6]-Dehydroparadol (M15) (5-80 µM; 24 h) inhibits the growth of HCT-116 and H-1299 cells, with IC 50 s of 43.02 and 41.59 µM, respectively. (E)-[6]-Dehydroparadol (10-40 µM; 24 h) induces apoptosis in HCT-116 and H-1299 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo (E)-[6]-Dehydroparadol (compound 19) (5 µM; 24 h) enhances Tg[glutathione S-transferase pi 1 (gstp1):green fluorescent protein (GFP)] fluorescence signal in the Tg(gstp1:GFP) transgenic zebrafish embryos. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Nrf2
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(E)-[6]-Dehydroparadol
CAS number：878006-06-5 molecular formula：C17H24O3
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| Chinese alias | (E)-[6]-脱氢表雄酮 | ||
| English alias | - | ||
| CAS number | 878006-06-5 | molecular formula | C17H24O3 |
| molecular weight | 276.37 g/mol | Exact mass | ≥95% |
| PSA | 46.500 Ų | logp | 4.700 |
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