Amifostine thiol (WR-1065) 是细胞保护剂 Amifostine 的活性代谢物。Amifostine thiol 是一种具有辐射防护能力的细胞保护剂。Amifostine thiol 通过 JNK 依赖的信号通路激活 p53。 Amifostine thiol (WR-1065) is an active metabolite of the cytoprotector Amifostine . Amifostine thiol is a cytoprotective agent with radioprotective abilities. Amifostine thiol activates p53 through a JNK-dependent signaling pathway .
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Amifostine thiol
CAS number:31098-42-7 molecular formula:C5H14N2S
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| Chinese alias | 阿米福汀硫醇 | 氨磷汀硫化物 | ||
| English alias | CHEBI:72583 | HY-137864 | AKOS006273087 | Q27104998 | WR1065 | WR-1065 | N-benzyl-N,N-dimethyl-2-(2-(4-(2,4,4-trimethylpentan-2-yl)phenoxy)ethoxy)ethan-1-aminium chloride | NCI60_016501 | N-(2-mercaptoethyl)-1,3-diaminopropane | ||
| CAS number | 31098-42-7 | molecular formula | C5H14N2S |
| molecular weight | 134.24 g/mol | Exact mass | ≥96% |
| PSA | 39.100 Ų | logp | -0.500 |
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