Bragsin2 是一种有效、选择性、和非竞争性的核苷酸交换因子BRAG2抑制剂,IC50值为 3 μM。Bragsin2 结合于 BRAG2 的 PH 结构域和磷脂双分子层的界面处,导致 BRAG2 无法激活磷脂化的 Arf GTPase。Bragsin2 能够影响乳腺癌干细胞。
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Bragsin2
CAS number:342795-08-8 molecular formula:
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 342795-08-8 | molecular formula | |
| molecular weight | 289.160 g/mol | Exact mass | ≥99% |
| PSA | 81.400 Ų | logp | 2.200 |
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