CAS number：299173-64-1 molecular formula：C28H42N2O7
17-Demethoxy-reblastatin (17-DR) is an inhibitor for heat shock protein 90 ( Hsp90 ) , with an IC 50 of 1.82 μM for yeast Hsp90 ATPase. 17-Demethoxy-reblastatin inhibits the proliferation of cancer cell HepG2 and SMMC7721, reduces the colony formation, and induces apoptosis through mitochondria and caspase mediated pathway.
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| CAS number | 299173-64-1 | molecular formula | C28H42N2O7 |
| molecular weight | 518.64 g/mol | Exact mass | - |
| PSA | - | logp | - |
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