CAS number：1124329-14-1 molecular formula：C24H32N6O3
AZ3146是单极纺锤体1（Mps1）激酶抑制剂，IC50为35 nM，对FAK，JNK1，JNK2和Kit的抑制性较弱。A potent and selective monopolar spindle 1 (Mps1) kinase inhibitor AZ3146 is a potent and selective monopolar spindle 1 (Mps1) kinase inhibitor (IC50 = 35 nM); less potent to FAK, JNK1, JNK2, and Kit. A potent and selective monopolar spindle 1 (Mps1) kinase inhibitor
| Chinese alias | - | ||
| English alias | AKOS024457919 | SW219317-1 | HY-14710 | CCG-264989 | AZ3146 | AZ-3146 | 9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one | NCGC00263090-01 | AZ 3146 | AU5 | J-002776 | J-519504 | PD136235 | AC-27407 | 9-Cycl | ||
| CAS number | 1124329-14-1 | molecular formula | C24H32N6O3 |
| molecular weight | 452.55 g/mol | Exact mass | - |
| PSA | 83.100 Ų | logp | 3.200 |
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