CAS number：714272-27-2 molecular formula：C19H20N4O2
Plinabulin (NPI-2358)是一种vascular disrupting agents(VDA)（血管阻断剂），作用于肿瘤细胞，影响微管蛋白解聚，IC50为9.8~18 nM。Phase 1/2。 Plinabulin (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing with IC50 of 9.8~18 nM in tumor cells. Phase 1/2.
| Chinese alias | - | ||
| English alias | TRIBENOSIDE [MI] | DB05992 | 986FY7F8XR | HMS3884P14 | plinabulinum | Dibenzyl N, N-diisopropyl-phosphoramidite | Plinabulin(NPI-2358) | 2,5-Piperazinedione, 3-((5-(1,1-dimethylethyl)-1H-imidazol-4-yl)methylene)-6-(phenylmethylene)-, (3Z,6Z)- | BPI 2358 | | ||
| CAS number | 714272-27-2 | molecular formula | C19H20N4O2 |
| molecular weight | 336.39 g/mol | Exact mass | ≥97% |
| PSA | 86.900 Ų | logp | 2.8 |
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