KF38789 选择性抑制 P-selectin 与 PSGL-1 结合。KF38789 抑制 U937 细胞与 P-selectin 免疫球蛋白 G 嵌合蛋白 (P-selectin-Ig) 结合,IC50 值为 1.97 μM。 KF38789 is a selective inhibitor of P-selectin-PSGL-1 binding. KF38789 inhibits the binding of U937 cells to immobilized P-selectin immunoglobulin G chimeric protein (P-selectin-Ig) with an IC50 value of 1.97 μM.
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KF 38789
CAS number:257292-29-8 molecular formula:C19H21NO5S
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Specs
| Chinese alias | 3-[7-(2,4-二甲氧基苯基)-2,3,6,7-四氢-1,4-噻嗪-5-yl]-4-羟基-6-甲基-2H-吡喃-2-酮 | ||
| English alias | 3-[7-(2,4-dimethoxyphenyl)-1,4-thiazepan-5-ylidene]-6-methylpyran-2,4-dione | 2H-Pyran-2-one, 3-[7-(2,4-dimethoxyphenyl)-2,3,6,7-tetrahydro-1,4-thiazepin-5-yl]-4-hydroxy-6-methyl- (9CI) | 4-(tert-butyloxycarbonyl)piperazin-2-one | 3-[7-(2,4-Dimethoxy-phen | ||
| CAS number | 257292-29-8 | molecular formula | C19H21NO5S |
| molecular weight | 375.44 g/mol | Exact mass | ≥97%(HPLC) |
| PSA | 103.000 Ų | logp | 2.200 |
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