compound introduction
PDM 2是白藜芦醇的类似物，可作为有效的选择性芳基烃受体（Ah受体，AhR）拮抗剂。Ah受体是依赖配体的细胞内转录因子，其配体包括一些异生物素，包括二恶英，苯并[a]，以及来自烟灰和煤焦油的多种多环芳烃。 PDM2 是一种选择性的高亲和力芳烃受体 (AhR) 拮抗剂，Ki 为 1.2±0.4 nM。 Product Describtion: PDM 2 is an analog of resveratrol acting as a potent and selective Aryl Hydrocarbon Receptor (Ah Receptor, AhR) antagonist. The Ah Receptor is a ligand-dependent intracellular transcription factor whose ligands include some of the most infamous xenobiotics, including dioxin, benzo[a]pyrene, and numerous polyaromatics from soot and coal tar. PDM2 is a selective, high-affinity aryl hydrocarbon receptor (AhR) antagonist with an Ki of 1.2±0.4 nM.
