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2-Iminobiotin hydrobromide

CAS number:76985-52-9    molecular formula:C10H18BrN3O2S

overview

compound introduction

2-Iminobiotin hydrobromide (Guanidinobiotin hydrobromide) is a biotin (vitamin H or B7) analog. 2-Iminobiotin hydrobromide is a reversible nitric oxide synthases inhibitor with K i s of 21.8 and 37.5 μM for murine iNOS and rat n-cNOS , respectively 2-Iminobiotin hydrobromide superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage . In Vitro Application of low concentrations of 2-Iminobiotin (2-IB; 10 ng/mL and 30 ng/mL) superimposed on hypothermia abrogates the hypoxia-induced lactate dehydrogenase (LDH) increase, resulting in LDH levels that were not different from the normoxia control. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:NO synthases

Specs

Chinese alias2-亚氨基生物素氢溴酸盐
English alias-
CAS number76985-52-9molecular formulaC10H18BrN3O2S
molecular weight324.24 g/molExact mass≥98%
PSA-logp-

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