CAS number：943319-70-8 molecular formula：C29H27F3N6O
Ponatinib (AP24534)是一种新型有效的作用于Abl， PDGFRα， VEGFR2， FGFR1和Src的多靶点抑制剂， IC50分别为0.37 nM， 1.1 nM， 1.5 nM， 2.2 nM和5.4 nM。A Bcr-Abl (Bcr and c-Abl fusion), FGFR, and Flk-1 inhibitor Ponatinib (AP24534) is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM, respectively. A Bcr-Abl (Bcr and c-Abl fusion), FGFR, and Flk-1 inhibitor
| Chinese alias | - | ||
| English alias | 4340891KFS | BDBM50322535 | Dithioglycerol (VAN) | 3-[2-(imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | 3-(2-(IMIDAZO(1,2-B)PYRIDAZIN-3-YL)ETHYNYL)-4-METHYL-N-(4-((4-METHYLPIPERAZ | ||
| CAS number | 943319-70-8 | molecular formula | C29H27F3N6O |
| molecular weight | 532.57 g/mol | Exact mass | - |
| PSA | 65.800 Ų | logp | 4.100 |
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