CB7993113 是一种有效的AHR拮抗剂,IC50为 0.33 μM。 CB7993113 直接结合 AHR 蛋白并阻断 AHR 核转位。 CB7993113 可分别抑制多环芳烃 (PAH) 和 TCDD 诱导的报告基因活性 75% 和 90%。
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2-((2-(5-bromofuran-2-yl)-4-oxo-4H-chromen-3-yl)oxy)acetamide
CAS number:819827-50-4 molecular formula:
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 819827-50-4 | molecular formula | |
| molecular weight | 364.150 g/mol | Exact mass | ≥98% |
| PSA | 91.800 Ų | logp | 2.400 |
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